The University of Adelaide CENTRE FOR AUTOMOTIVE SAFETY RESEARCH

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TitleCorrelation of postmortem MRI and CT appearances with neuropathology in brain trauma: a comparison of two methods
AuthorsJones NR, Blumbergs PC, Brown CJ, McLean AJ, Manavis J, Perret LV, Sandhu A, Scott G, Simpson DA
Year1998
TypeJournal Article
AbstractPostmortem magnetic resonance (MR) scans were performed on the brains of 12 victims of fatal head injuries. These were compared with neuropathological studies of the entire brain. The first six subjects were imaged with the brain in situ and comparison was also made with antemortem computed tomography (CT). The brains from the subsequent six subjects were removed at autopsy, fixed in formalin and then imaged in a mitre box designed to overcome the problems encountered in the pilot study. Although both CT and MR imaging (MRI) detected all clinically relevant haemorrhagic lesions, many pathologically significant lesions were missed. MRI detected many more lesions than CT, but still failed to visualize areas of non-haemorrhagic axonal injury.
Journal TitleJournal of Clinical Neuroscience
Journal Volume (Issue)5(1)
Page Range73-79
Page Count8
Notesavailable from CASR library on request

Reference
Jones NR, Blumbergs PC, Brown CJ, McLean AJ, Manavis J, Perret LV, Sandhu A, Scott G, Simpson DA (1998) 'Correlation of postmortem MRI and CT appearances with neuropathology in brain trauma: a comparison of two methods', Journal of Clinical Neuroscience, 5(1), pp 73-79.